So, I have a character with a extremely experienced tamed Giant Ant Queen (picked her up from PC:2, named her Lucy). She and I are exploring the CoC together, and find an ant hill in D:5. Lucy went up to a giant ant worker, attacked it, and then became hostile and attacked me. I was able to tame her again with music, but every time she or I attacked an ant, she would go psycho again. I eventually had to leave her off level while I cleared the nest.