Alchemical explosion hair trigger
It's too easy to accidentally perform alchemy, and doing so will almost certainly result in an explosion.
Skills [a] -> Alchemy [a] -> Ingredient [a] -> Ingredient [a] -> Kaboom.
This means holding down [a] for even a slit second is likely instant death.
Adding a [y/n] confirmation after selecting ingredients would help. (e.g. "Do you really want to use alchemy to combine X and Y?")