A couple of my favorites:

Hurthling Anything: Combine a race that always starts with Food Preservation, Cooking, and a cooking set with deities that like cooked meals, and you can get some of the easiest precrowns of the game.

Hurthling Druids: Almost no problem with cats. Non-hostile ants on PC2 give a huge supply of ammo.

Candle-born Female Hurthling Thieves: Heir Gift, starts with the full complement of thief skills. Particularly useful if you remember that Pick Locks works for locking doors as well as unlocking them.

Raven-born Drakeling Monk: Every aspect of the Starsign pairs well with this race/class combo: Lightning fast, quicker access to an awesome artifact (and you have so much DV, it doesn't matter that it's a 2-handed weapon) and you even start with music so you can take advantage of the "more powerful companions" if you choose.

High-Elf Assassin: Let the poisoned arrows fly!