I find that most of the time I set tactics to berserk, the only downside to this is that you get a big discount on DV.
By doing this you mostly kill opponents in one turn, so the loss in DV is mostly not a factor. If you do get hit because you did not kill the opponent and it gets a damaging shot in, the lost HP is quickly recovered by spenseweed anyway.
I feel like suggesting that setting tactics to berserk has some more drawback. Either there is a chance of the weapon slipping out of your hand scaling with strength, the lower the PC's strength bigger the chance or/and a chance for the weapon to break scaling with strength of the PC and material of the weapon(eternium will almost never break)?