I played for more than 10 years without touching d50, but a week ago managed to achieve absolutely casual victory with a very first Mist elf / Priest / Heir combination.

Only real issues I stumbled on were accidentally angering Casino shop guys and poison hands corruption w/o thick gauntlets. Oh, and also "Your skin is destroyed by the touch of impure metal." spam accompanied with teleportisis transformed the process of reading books into a funny minigame, where you have to press space until it is time to teleport, then space again, then y, then repeat.

I relied heavily on my mace during early game, Rolf's Companion / Saviour combination in mid game and my crowning gift "Skull Crusher" in late game, while maintaining axe as a range weapon, cause I literally encountered only around 4 to 5 bows and crossbows in the whole game (and they got burned like in 20 minutes every time I equipped them).
Also I spent my two wishes on rings of ice and spellbooks of Rain of Sorrow (nearly wasted wish for Acid Ball), which I used to kill most bosses (and then I ate them. All of them).

I spent Immune to Pain talent on the Ironfist (until the poison hands attacked).

What can I say about this run in general? It felt casual, but I still was extremely concentrated from the entering of SMC to the final blow on Riurry. As you can see (or not if I managed to remove all non-important staff), I did not even bothered to sort my inventory, replace thick gauntlets with Ironfist, drink some potions for score etc.

Code:
~ ➤ cat weed_pri.flg
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                                 Screenshot
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        ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^+^^^^^^   ^^^
         ^^^^     ^^^  ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^

Weed priest   St:27  Le:32  Wi:24  Dx:31  To:20  Ch:19  Ap:30  Ma:40  Pe:12 L+
DV/PV: 37/50   H: 266(266)    P: 652(652)    Exp: 43/14719301  DrCh   Sp: 134
Blessed Invisible Burdened Berserk
------------------------------------------------------------------------------


----------------------------------------------------------------------------
                            Background Information
----------------------------------------------------------------------------

Name: Weed priest         Race: female Mist Elf     Class: Priest
Eye color: white          Hair color: silver        Complexion: white
Height: 6'4"              Weight: 61 pounds
Age: 8330 (grown-up, 5 years of unnatural aging added in)
Star sign: Candle         Birthday: 3/Candle (day 273 of the year)

YOUR HISTORY:
        You remember rising from the Mists... so long ago. Your brethren
 welcomed you into your physical existence and cared for you until you
 managed to cope on your own. Thus decades passed.
        As a young child you were taught by the elders of your race. They
 showed to you the whole breadth of creation and opened your mind to
 encompass whatever your life goal would become. Thus centuries passed.
        You spent your youth honing your skills and preparing for the
 ultimate quest that would change you forever: the trip to the mists of
 Destiny. Thus millennia passed and empires rose and fell.
        As a young adult your community prepared you for the final step
 towards adolescence: your Destiny Quest in the Mists of Time. In the full
 knowledge that this quest would change you forever you finally entered the
 Mists that birthed you and emerged changed... as decreed by the Dreamers
 from Beyond.
        You decided to become a Priest.


----------------------------------------------------------------------------
                                  Inventory
----------------------------------------------------------------------------
Total weight: 5528 stones                Carrying capacity: 6675 stones

He: blessed eternium cap [+0, +4]                                     [28s]
Ne: blessed ankh                                                       [3s]
Bo: blessed robes of resistance (-4, -4) [+3, +12] {To+5}             [60s]
Gi: blessed girdle of carrying [+0, +0]                               [15s]
Cl: uncursed Brannalbin's Cloak of Defense [+3, +3]                   [30s]
RH: blessed dwarven shield "Rolf's Saviour" (+2) [+9, +6]            [120s]
LH: blessed rune-covered club "Skullcrusher" (+12, 3d6+2) [-3, +0] {St+4}
RR: blessed ring of slaying (+9 melee damage, +6 missile damage)       [1s]
LR: blessed ring of the High Kings [+2, +3]                            [1s]
Br: uncursed bracers of protection [+0, +5]                           [10s]
Ga: uncursed thick gauntlets (-1, -2) [-2, +3]                        [15s]
Bo: uncursed eternium boots [+0, +5]                                  [55s]
MW: -
Mi: blessed dwarven rune axe "Rolf's Companion" (+3, 3d6+6) [+4, +4] {To+3}
Tl: heap of 19 blessed spenseweeds                                    [38s]


----------------------------------------------------------------------------
                                    Stuff
----------------------------------------------------------------------------

Total weight: 4982 stones   Carrying capacity: 6675 stones

Helmets ('[')
   uncursed crown of lightning [+0, +1] (+5 spd)                      [65s]
   heap of 2 uncursed eternium caps [+0, +4]                          [56s]
Armor ('[')
   blessed ancient mummy wrapping [+1, +5] {Ap-8}                     [60s]
   uncursed Perion's mithril plate mail (-1, -4) [-1, +13]           [450s]
Gauntlets ('[')
   uncursed elemental gauntlets (-1, +0) [+0, +3]                     [10s]
   blessed iron gauntlets "Ironfist" (-1, +0) [+1, +3] {St+7}         [10s]
   uncursed thick gauntlets (-1, -2) [+0, +1]                         [15s]
Girdles ('[')
   uncursed eternium girdle [+0, +6]                                  [12s]
Boots ('[')
   uncursed eternium boots (+1, -1) [+2, +5]                          [55s]
   uncursed eternium boots [+0, +5]                                   [55s]
One-handed weapons ('(')
   blessed swift eternium mace of the sun (+0, 2d6+8)                 [55s]
   uncursed black rune-covered dagger "Needle" (+8, 3d4) [+4, +1]     [10s]
   uncursed pick axe of surrendering (-1, 1d6+1)                      [75s]
Books ('"')
   uncursed weird tome                                               [100s]
Valuables ('$')
   13485 gold pieces                                                 [134s]

----------------------------------------------------------------------------
                                Weapon Skills
----------------------------------------------------------------------------

Melee weapon           Lvl   Hit   Dam   DV   Level          Required marks
---------------------  ---   ---   ---   --   -------------  --------------
Unarmed fighting         1    +1    +0   +0   basic                37
Daggers & knives         1    +1    +0   +0   basic                37
Clubs & hammers         11   +10    +7   +4   Mastery              1856
Maces & flails           9    +7    +5   +3   excellent            1747
Swords                   1    +1    +0   +0   basic                37
Axes                    10    +9    +7   +3   excellent            745
Whips                    1    +1    +0   +1   basic                37
Pole arms                1    +1    +0   +0   basic                37
Twohanded weapons        1    +1    +1   +0   basic                37
Staves                   1    +1    +0   +1   basic                37

Missile weapon         Lvl   Hit   Dam   Ra   Level          Required marks

---------------------  ---   ---   ---   --   -------------  --------------
Slings                   0    +0    +0   +0   unskilled            10
Bows                     3    +6    +4   +1   basic                13
Crossbows                0    +0    +0   +0   unskilled            10
Thrown axes & hammers    4    +8    +6   +1   skilled              29
Thrown daggers           0    +0    +0   +0   unskilled            10
Thrown rocks & clubs     0    +0    +0   +0   unskilled            10
Thrown spears            0    +0    +0   +0   unskilled            10
Boomerangs & scurgari    0    +0    +0   +0   unskilled            10

Shields                Lvl   DV               Level          Required marks

---------------------  ---   ---              -------------  --------------
Shields                  7   +14              skilled              527

Damage caused with your melee weapons:
--------------------------------------
Left hand: +138 bonus to hit, 3d6+44 damage

Damage caused with your missile weapons:
----------------------------------------
Ammunition: 1, base range: 4, +56 bonus to hit, 3d8+31 damage




----------------------------------------------------------------------------
                                   Skills
----------------------------------------------------------------------------

  Alertness .................100    (superb)       [+1]
  Athletics ................. 48    (fair)         [+2d4] # Scroll of education?
  Backstabbing ..............100    (superb)       [+1d3]
  Climbing ..................100    (superb)       [+1d3]
  Concentration .............100    (superb)       [+2d4]
  Courage ...................100    (superb)       [+1d5]
  Detect item status ........100    (superb)       [+2d4]
  Detect traps .............. 84    (great)        [+1d3]  # Scroll of education?
  Dodge ..................... 63    (good)         [+1]  # Scroll of education?
  First aid .................100    (superb)       [+2d4]
  Haggling .................. 73    (great)        [+3d3]
  Healing ...................100    (superb)       [+2d4]
  Herbalism .................100    (superb)       [+2d4]
  Listening .................100    (superb)       [+4d4]
  Literacy ..................100    (superb)       [+2d4]
  Music ..................... 89    (great)        [+1d5]
  Necromancy ................ 81    (great)        [+1d3] # Why I even spent points on this?
  Stealth ...................100    (superb)       [+1]
  Swimming .................. 76    (great)        [+1d3]
  Tactics ...................100    (superb)       [+1]
  Two weapon combat ......... 89    (great)        [+1] # Why I even spent points on this?

----------------------------------------------------------------------------
                                   Spells
----------------------------------------------------------------------------

   Baptism of Fire          :   737,   4pp     (Effectivity: +43) # Best spell
   Cure Critical Wounds     :  2192,   7pp     (Effectivity: +12)
   Disarm Trap              :   490,   5pp     (Effectivity: +9)
   Divine Digger            :   572,  50pp     (Effectivity: +4)
   Divine Wrath             :   884,   6pp     (Effectivity: +22)
   Earthquake               :  1023,  40pp     (Effectivity: +3) # More than 10 times triggered this instead of Divine Wrath
   Ethereal Bridge          :   653,  14pp     (Effectivity: +15)
   Freezing Fury            :   944,  12pp     (Effectivity: +5)
   Greater Divine Touch     :   537,  50pp     (Effectivity: +2) # Discovered I had this since midgame
   Knowledge of the Ancients:   488,  20pp     (Effectivity: +8)
   Major Punishment         :    25,  17pp     (Effectivity: +9)
   Nether Bolt              :  2005,   6pp     (Effectivity: +18)
   Petrification            :   761,  60pp     (Effectivity: +1)
   Rain of Sorrow           :   352,  17pp     (Effectivity: +10) # Wished for books

----------------------------------------------------------------------------
                              Her further life:
----------------------------------------------------------------------------

After she leaves the Drakalor Chain she is welcomed by her people with great
honors. They acknowledge her noble deeds, her valor, her cunning and her
great skills that helped to prevent the complete destruction of the world
she knows. She is crowned to be the queen of all mist elves and lives a long
and prosperous life full of love, happiness and pleasure.

----------------------------------------------------------------------------
              Her achievements during her battles:
----------------------------------------------------------------------------

Weed priest, the mist elven priest, saved the world with her brave efforts
and became a great ruler while saving herself 8 times.
She scored 10282836 points and advanced to level 43.
She survived for 0 years, 103 days, 15 hours, 45 minutes and 46 seconds
(127451 turns).
Weed priest visited 178 places.
Her strength score was modified by +11 during her career.
Her learning score was modified by +10 during her career.
Her willpower score was modified by +10 during her career.
Her dexterity score was modified by +16 during her career.
Her toughness score was modified by +5 during her career.
Her charisma score was modified by +11 during her career.
Her appearance score was modified by +9 during her career.
Her mana score was modified by +15 during her career.
Her perception score was modified by -5 during her career.
She was unnaturally aged by 5 years.
She was the champion of the arena.
She defeated the arch enemy of a mighty karmic wyrm.
She left the Drakalor Chain after completing her quest and became a great
leader and famous heroine.
7807 monsters perished under her attacks.
The following 28 artifacts were generated during her adventure:
  the si
  the dwarven rune axe "Rolf's Companion"
  the scythe of corruption "Moon Sickle"
  the golden gladius "Death's Sting"
  the dwarven shield "Rolf's Saviour"
  the Chaos Orb of Elemental Water
  the Chaos Orb of Elemental Air
  the Chaos Orb of Elemental Fire
  the Chaos Orb of Elemental Earth
  the heavy cudgel "Black Thumb"
  the lead-filled mace "Big Punch"
  Brannalbin's Cloak of Defense
  the elemental gauntlets
  the ring of the High Kings
  the crown of science
  the ancient mummy wrapping
  the ankh
  Perion's mithril plate mail
  the black torc
  the rune-covered club "Skullcrusher"
  the glaive "Long Sting"
  the Chaos Orb of Elemental Mana
  the black rune-covered dagger "Needle"
  the robes of resistance
  the iron gauntlets "Ironfist"
  the weird tome
  the rune-covered halberd "Wyrmlance"
  the tome of donors
She possessed the following intrinsics:
  She was fire resistant (also through items).
  She was poison resistant (also through items).
  She was cold resistant (also through items).
  She was acid resistant (also through items).
  She was lucky (also through an item).
  Fate smiled upon her (also through an item).
  She was petrification resistant.
  She was able to teleport.
  She was able to control teleportation.
  She was invisible (gained through an item).
  She was stun resistant (also through an item).
  She was paralyzation resistant.
  She was resistant to death rays.
  She was shock resistant (also through items).
  She was able to see invisible things.
  She was immune to shock attacks.
  She was able to resist confusion attacks (also through an item).
She had the following talents: Boon to the Family, Careful, Charged,
Charming, Defensive Fighter, Good Book Learner, Good Learner, Hardy, Heir,
Immune to Pain, Iron Skin, Long Stride, Potent Aura, Quick, Steel Skin,
Strong Thrower, Tough Skin.
She had a final speed score of 134 (final base speed: 139).
She was a messiah of Order.
She asked for 10 divine interventions.
She was a holy champion of Order.

The following monsters were vanquished:
      3 ancient black dragons
     56 ancient blue dragons
      1 ancient blue wyrm
      1 Ancient Chaos Wyrm
      4 ancient karmic dragons
      8 ancient minotaurs
      3 ancient red dragons
      1 Ancient Stone Beast
      6 ancient white dragons
      9 animated armors
    257 animated trees
      3 balors
      1 banshee
     53 blue dragons  # Insanely annoying
      1 bunny master
      7 casino guards
      1 cat lord
      1 Chaos Archmage
      1 chaos diplomat
     20 chaos knights
     10 chaos lizards
     85 chaos mutants
     12 chaos plague bearers
    192 chaos servants
     21 chaos sisters
      6 chaos spawn
     35 chaos spiders
      4 chaos vipers
      1 chaos warlord
     16 chaos warriors
     26 chaos wizards
    133 claw bugs
      9 corruptors
      1 crime lord
      9 death oozes
      9 diamond golems # Those were tough
      7 doppelganger kings
      7 doppelganger lords
      2 Dorn Beasts
      1 dwarven artificer
     44 dwarven chaos knights
      1 emperor lich
      1 farmer # What?
     50 frost giant jarls
      1 ghost king
      5 gorgons
      5 great blue wyrms
      1 great karmic wyrm
      1 greater black unicorn
    107 greater chaos servants
      2 greater molochs
      8 hydras
      1 karmic dragon
     13 liches
     24 lich kings
     19 lightning lizards # Insanely annoying
     15 magebane eyes
     15 magedoom eyes
     40 master liches
      1 master necromancer
      1 Master Summoner
      9 mimic hiveminds
      1 minotaur mazelord
      1 minotaur mazemaster
      8 molochs
      1 mummy lord
     99 ogres
      2 ogre emperors
      4 quicklings
      5 quickling kings
      3 quickling lords
      6 quickling queens
      2 red dragons
      5 shadow wyrms
      2 skeletal kings
      1 Snake from Beyond
      4 titans
      1 undead chaos dwarven berserker
     56 vampires
      4 white dragons
      1 white unicorn
    108 wights
     93 wraiths
     24 writhing masses of primal chaos
    104 zombies

Dispatched the legendary vampire Torlo.
Dispatched the legendary troll Nanji.


----------------------------------------------------------------------------
                               Playing Time
----------------------------------------------------------------------------

You played for 37 hours, 4 minutes and 39 seconds.


----------------------------------------------------------------------------
                             Version Information
----------------------------------------------------------------------------

Ancient Domains Of Mystery
Release 72
OSX Deluxe (Steam) Build: Oct 16 2016 14:22:24
PS The name of my character, as well as his main tool, is a reference to the Sleep's stoner masterpiece album "Dopesmoker".