Guaranteed ring of ice. Change to xp curves means you usually reach the ToEF a couple levels higher. Massive boost to Maze rewards. Gardening is good enough that it's worth it to skip healing if you start with herbalism now. Stealth is awesome. Fletchery is useful. First aid is much better. Summoners massively toned down. Average artifact quality is higher, IMHO. Thunderstroke and True Aim are amazing. Corruption rate is basically negligible. Less food consumption from encumbrance. Platinum girdle much easier to get. Healing potions and power scrolls are much better.
Hoping to win with every class, doomed. Archer, Barbarian, Bard, Beastfighter, Druid, Elementalist, Farmer, Fighter, Monk, and ULE Priest down.