Sounds interesting, but probably very tough. A lot of very nice items, including virtually all artifacts, as well as piety to a significant extent, would be off limits, and the ToEF with 10 points of damage per turn would be brutal. Maybe a healer would be better than a wizard for uber regeneration?
I'd say key points are as follows:
Alertness is mandatory. High level dragons and wyrms can do several hundred points of damage with breath attacks; lack of death ray resistance, petrify resistance (although gorgons are blessedly rare), etc. would also cause serious problems without it.
Starvation scumming will probably be essential--you need to get Wi into the stratosphere to resist confusion from high level mobs, esp. since prayers will be worthless for this challenge.
Astral planes corruption is basically automatic shift-Q unless you have corruption removal available.
Hoping to win with every class, doomed. Archer, Barbarian, Bard, Beastfighter, Druid, Elementalist, Farmer, Fighter, Monk, and ULE Priest down.